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Anecdotal/observational reports (body composition, energy, recovery) exist in performance settings, but lack standardized dosing, controls, and validated endpoints

If a person is very deficient in B12 or has high-stress levels, the benefits from the shot may last up to three to four days

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The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure

Research shows the compound can induce fat loss without affecting food intake, giving researchers a tool to study metabolic rate independent of appetite mechanisms