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Adverse events occurred in 13 (32.5%), all mild and transient
GLP-1 RAs promote diuresis and natriuresis by inhibiting sodium reabsorption in the renal proximal tubule through the Na + /H + exchanger isoform 3 (NHE3) [77]
That really captures how little innovation theres been. Reville says that GLP-1s have many advantages: They appear to work across all substances, patients dont have to be abstinent to start treatment, and its easy to self-administer the weekly dose
