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Although the specific epigenetic regulatory mechanisms remain incompletely understood, evidence suggests that epigenetic factors, including miRNAs and RNA methylation, may play a role in the therapeutic process by regulating key genes associated with ferroptosis, such as GPX4 and SLC7A11 (200)

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They are not from clinical trials, are not incidence rates, and are frequently inconsistent a meaningful share of community reports describe no noticeable effects at all

SB-01 clinical trials: The synthetic peptide SB-01, which targets TGF-beta-1 signaling in degenerated discs, is currently in clinical trials