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A network meta-analysis of 22 randomized controlled trials covering 2,258 participants found GLP-1 receptor agonists reduced lean mass by a mean of 0.86 kg , published in Metabolism
Rybelsus is the only oral GLP-1 medication approved in Canada
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In their study, the authors present a framework that looks at the occurrence of dysbiosis in aging populations and how it is characterized by reduced SCFA production, depletion of beneficial bile acids, and increased translocation of lipopolysaccharide (LPS)
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