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Search terms included free-text keywords and Medical Subject Headings (MeSH) terms related to polysaccharides, rheumatoid arthritis, and gut microbiota. These terms were used in various combinations for title/abstract or full-text searches, for instance: polysaccharides AND rheumatoid arthritis AND gut microbiota (search strategy can be found in Supplementary Table 1 )
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To investigate the effect of gene knockout on l-cysteine and GSH degradation, the engineered strains were cultured in the flasks as described above and the cells were collected by centrifugation (6000 rpm, 4 C for 5 min) after two washes with 50 mM phosphate buffer (pH7.0)
The study was conducted in mice and the finding is mechanistically plausible given ghrelin's known orexigenic and lipogenic effects
No direct interactions are reported, yet combining these medications may increase the risk of hypoglycemia and potential side effects
Wegovy, on the other hand, is FDA-approved just for weight management
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