eli lilly retatrutide clinical trials Lilly's triple agonist achieves 16.8% weight loss in phase 3 trial Retatrutide, Eli Lilly's next obesity

Semaglutide brands like Ozempic and Wegovy do not come with warnings on increased risks of deep vein thrombosis despite research studies linking these adverse effects to GLP-1 RA drugs

Exenatide, on the other hand, should be avoided in patients with severe renal impairment (CrCl less than 30 mL/min)

From a cardiovascular perspective, stacking GLP-1 agonists would likely produce additive heart rate effects, which is another reason to avoid the combination

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Gut adjusting = progress

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