Unfortunately, the CNS penetration is greatly hampered by the blood-brain barrier (BBB)
Sharma R, Biedenharn KR, Fedor JM, Agarwal A
Coming from someone who spent 25 years treating the same patients with diet and behavior alone, that's a meaningful verdict
Traverso, N., et al., Role of Glutathione in Cancer Progression and Chemoresistance
Several licensed weight management injectable therapies are available in the UK including semaglutide (Wegovy, approved by NICE for weight management in eligible adults) and tirzepatide (Mounjaro, licensed in the UK for type 2 diabetes and, subject to current NICE guidance, for weight management in eligible adults)
Compounded semaglutide injections are $189/mo month-to-month, or from $149/mo on the 6-month plan, and your dose may increase over time without a price change, making multi-month budgeting predictable