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Evidence KPV has mechanistic NF-B data, small clinical studies in IBD using oral delivery, and atopic-dermatitis research using topical or oral delivery

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Its clinical development for obesity was discontinued in 2007 after the pivotal 536-participant Phase IIb trial failed to meet its primary efficacy endpoint, and no formulation of the compound has received FDA approval since

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It is helpful in preventing fatigue and may also be useful in some cases of allergies because it reduces histamine release