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In brief, FLS were incubated with 5 M Fluo-4-AM for 30 min, and the intracellular influx of calcium was observed under an LSM700 laser scanning confocal microscope (Zeiss, Germany) at a 1/s frequency

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As with all medications, GLP-1 receptor agonists carry potential adverse effects, most commonly gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation

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CagriSema is given as a once-weekly injection under the skin

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