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The GLP-1 analogs liraglutide and semaglutide reduce atherosclerosis in ApoE(/) and LDLr(/) mice by a mechanism that includes inflammatory pathways
Any off-label use (such as for weight loss) should be discussed with a licensed healthcare provider
If youre newer to prescribing or supporting GLP-1 therapy, Ive put together a four-part series covering key considerations, including initiation, weight management, cost, and side effect mitigation
De-escalation strategies in HER2positive early breast cancer (EBC): final analysis of the WSG-ADAPT HER2+/HR- phase II trial: efficacy, safety, and predictive markers for 12 weeks of neoadjuvant dual blockade with trastuzumab and pertuzumab +/- weekly paclitaxel
Those of us who want GLP-1s for metabolic balance or recovery support dont fit the criteria
Others feel vague, and that can make the problem harder to name
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