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Since mitochondria are essential to our very existence, it is unsurprising that the effects of mitochondrial diseases can be severe, and sometimes lethal, spanning a wide-ranging spectrum of physiological and biochemical symptoms [1,3,4] (see Table 1 for examples)

Loose skin (e.g., on the belly or arms) is a common side effect of any major weight loss

P value: two-sided P value from Fishers exact test for test of no difference

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In the trial, people given the Wegovy tablet were significantly more likely to lose at least 5%, 10%, 15%, or 20% of their body weight than those given a placebo, making it an effective oral weight loss treatment