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AIDS Res Hum Retrovir (1996) 12:146371

A small subset of participants, approximately 12%, continued losing through week 48 without plateauing

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Lower levels of IGF-1 and growth hormone in older adults have been linked with (5, 14): increased fat mass increased cardiovascular risk decreased muscle mass and strength lower cognitive function lower bone density limited joint mobility Several of these traits are seen in frail older adults

But we also saw tremendous positive effects on function when you look at treadmill running for example, and mitochondrial proteins on the muscle level