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as an anti-ferroptotic factor that parallels the GSH system [82, 83]

J Cell Biochem 120(4):47324738

Glutathione is a powerhouse molecule produced naturally within our cells

doi: 10.3389/fphar.2025.1737199 Received 01 November 2025 Revised 21 December 2025 Accepted 29 December 2025 Published 15 January 2026 Volume 16 - 2025 Edited by Dawei Chen, University of Kiel, Germany Reviewed by Eveljn Scarian, University of Pavia, Italy Hong Cheng, Yangzhou University, China Updates Copyright 2026 Knudsen, Tadje, Coggins and Venketaraman

J Thorac Oncol 16(4):601-609, 2021

Results of cellular thermal shift assay and molecular docking indicate that GPX4 is a potential direct target of carnosine, and carnosine shows promise as a potential inhibitor of ferroptosis for the treatment of renal I/R injury and other conditions associated with ferroptosis