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Possibilities include: fecal SCFA levels (as an indicator of beneficial fermentation), serum TMAO (marker of detrimental microbial metabolism), gut permeability assays (like urinary sugar tests or blood zonulin) to gauge gut barrier integrity, and even gut microbial gene profiles that might predict rapid vs slow disease progression
This enhances mitochondrial function and reduces mitochondrial DNA leakage, resulting in decreased inflammatory cytokine release and improved vascular integrity in the retina ( 2.4.2 ECM remodeling Recent advances in research on eye disease pathogenesis have highlighted the significance of the ECMs standard structure and function
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