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In addition, the strict eligibility criteria could have limited the number of studies included, which compromises the generalizability of the results
doi: 10.1002/mrm.1910300604 58 HarrisADPutsNAEddenRA
References Svensson J et al., J Endocrinol Invest, 1998 21(9):692-699
had demonstrated in their study that CD133 + stem cells isolated from MCF-7 breast cancer cell lines, upon treatment with 0.001 and 0.1 M 1,25(OH) 2 D 3 , elevated the production of vitamin D receptors in the cancer stem cells by inhibiting the Wnt/-catenin signalling, concomitantly bringing down tamoxifen resistance in the MCF-7 cells [261]
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The alternative TFR2 isoform, TFR2, lacks the transmembrane and cytoplasmic domain but might be involved in the regulation of iron efflux in the MPS (57)
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