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Kelley N, Jeltema D, Duan Y, He Y
In its oxidized (NAD+) and reduced (NADH) forms, this coenzyme cycles between metabolic reactions, accepting and donating electrons during nutrient breakdown and ATP generation
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An RCT in patients receiving cisplatin chemotherapy found that NAC (1,200 mg/day) significantly reduced nephrotoxicity and ototoxicity without reducing antitumor efficacy (Riga et al., Am J Clin Oncol, 2013) [77]
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Chemical Engineering Journal, 439 , 135765
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