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Moreover, a single injection of semaglutide lowered BP in hypertensive Glp1r VSM+/+ but not Glp1r VSM/ mice, demonstrating that the BP-lowering response to semaglutide is preserved in a hypertensive setting (Figure 2, JL, PR, and VX)

Curr Neuropharmacol 14:101115 Fontanella RA, Ghosh P, Pesapane A, Taktaz F, Puocci A, Franzese M, Feliciano MF, Tortorella G, Scisciola L, Sommella E, Ambrosino C, Paolisso G, Barbieri M (2024) Tirzepatide prevents neurodegeneration through multiple molecular pathways

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Arch Dis Child 2013;98(12):9981003

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