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This method allows for absorption through the oral mucosa, bypassing some digestive breakdown and providing moderate systemic availability

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If the local pH environment is unsuitable, the peptide may show cloudiness, floating particles, clumping, gel-like behaviour, aggregation, or precipitation

The enzyme glutathione reductase (GR) , utilizing the coenzyme NADPH, steps in to break the disulfide bond, recycling GSSG back into the active, reduced GSH state

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