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2019;364:l476

Some people even have genetic defects that disrupt how they absorb and use vitamin D, so supplementation may be necessary to reach optimal levels

The leached amount would be attributed to the poor association/adsorption of a small fraction of the AuNCs with/at the surface of PLGA in resemblance to the known burst release of encapsulated drugs in PLGA nanohosts

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Clinicians will typically try standard prenatal vitamins or oral supplementation first, resorting to IM/IV B-complex therapy if those are inadequate or not feasible