The researchers found major aberrations in ROS clearance pathways, noting that Long COVID patients showed significantly lower levels of mitochondrial superoxide dismutase 2 (SOD2), a highly protective enzyme
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Glutathione is involved in tissue building and repair, making chemicals and proteins needed in the body and immune system function
Altered interactions of tryptophan metabolites in first-episode neuroleptic-nave patients with schizophrenia
However, our data suggest that following GSH depletion, NRF2 is stabilized, and this stabilization is associated with decreased expression of lipogenic enzymes and lower serum triglyceride levels