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The LIVE trial, conducted in stable HFrEF patients (with or without T2D), found no significant effect of liraglutide on the change in LVEF with increased arrhythmic events

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In individuals with Type 2 Diabetes (T2D), there is an observed increase in Gram-negative Enterobacteriaceae and a concurrent decrease in acetic acid-producing bacteria, such as Bifidobacteria