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Albuminuria categories were based on UACR

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Some researchers report usable potency beyond 28 days, but the safety margin narrows significantly after that point

Ensure the skin is fully dry before injection

Semaglutide was initiated at 0.25 mg per week for the first 4 weeks via a pre-filled pen injector, escalating in a fixed-dose regimen every 4 weeks to reach the maintenance dose of 2.4 mg by week 16 (lower maintenance doses were permitted if participants were unable to tolerate 2.4 mg) (Extended Data Fig

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