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Approximately 7% of participants in the Phase 2 clinical trial experienced skin sensitivity, compared to 1% in the placebo group

Dysregulated extracellular Ca 2+ promotes eosinophil transmigration and upregulates adhesion molecules CD11b/CD18, amplifying airway inflammation (126)

Early in the clinical development process, the PI3-AKT-mTOR pathway is one of the growing multi-targets of pharmaceuticals