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Tirzepatide is a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1RA) that has shown efficacy against MASH in some clinical trials
Mechanism-based research considerations include: Altered methylation: NNMT inhibition affects SAM, a participant in many methylation reactions
Tirzepatide and health-related quality of life in adults with obesity or overweight: Results from the SURMOUNT-3 phase 3 randomized trial
They may suggest a treatment to manage your symptoms
J., Brannon, A
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