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"Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes." New England Journal of Medicine 391.2 (2024): 109-121

Furthermore, clinical data suggested that microbial metabolites, particularly indole compounds, played a crucial role in hepatic lipid metabolism in the host [33, 34]

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Researchers found that, compared with healthy controls, the levels of trimethylamine oxide, glutamine, and lactic acid in the plasma of patients with depression were significantly increased, while the levels of phenylalanine, valine, alanine, glycine, leucine, citrate, choline, lipids, and glucose were significantly decreased