Research has explored whether NNMT inhibitions effects extend beyond direct enzyme activity to broader metabolic reprogramming, including observations of altered mitochondrial function, lipid oxidation, and gene expression in research models
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In addition, IGF-IR inhibition sensitizes cancer cells to other chemotherapeutic agents, such as paclitaxel, 5-fluorouracil (5FU), temozolomide, gemcitabine, and bortezomib [101,102,103,104,105]
Effect of L-carnitine and acetyl-L-carnitine on the human erythrocyte membrane stability and deformability