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The incidence was dose-dependent, meaning higher doses produced more frequent and more intense nausea episodes
Yes, there are
Patients experiencing persistent gastrointestinal adverse effects may benefit from slower titration schedules or maintaining lower doses for longer periods before attempting escalation
Despite its potential benefits and the evidence drawn from existing clinical trials on standard dosing, microdosing is generally not supported by FDA-approved dosing protocols
The sample was hydrated with 1 ml of 0.1 mM sodium acetate buffer (pH 4.5) and vortexed every 5 min for 20 min
( Prasa 2004 ) Symptoms of propionic acidemia include frequent vomiting, lethargy, refusal to feed, and hypotonia
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