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Over the past few years, GLP-1 receptor agonists have moved from diabetes treatment rooms to mainstream weight management conversations, and for good reason

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In addition, the methionine salvage pathway, the glyoxalase system, carnitine metabolism, and remnants of the carboxylic acid metabolism were described in erythrocytes, and a recent review compiled a map of erythrocyte metabolism that listed 83 enzymes and membrane transport systems as well as 129 metabolites and ions [182]

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First cardiovascular safety trial of a DPP-4 inhibitor in patients with T2DM and high cardiovascular risk, showing that saxagliptin does not augment MACE but increases hospitalization for heart failure