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In case of neurologic symptoms or abnormalities, it is suggested to administer hydroxocobalamin, 1000 mg once or twice weekly for a period of up to 2 years, and the package insert for hydroxocobalamin has included these particular instructions for several decades
S2CID 6994133
B12 works to metabolize homocysteine, an amino acid that at elevated levels is a well-established independent risk factor for heart disease and stroke
They are not illegal to buy or own - and widely available online - but they are not approved for human use, so are not subject to the quality controls that govern pharmaceutical manufacturing
10.1002/mds.27633 Mov
Yes, NAD+ treatments will take longer because they involve IV drips
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