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Accounts of Chemical Research, 1991, 24 9: 264-270

Cost is also a factor

Retinol is known for stronger renewal-style effects, while copper peptides are often chosen for a gentler, supportive approach to firmness, smoothness and skin comfort

10.1016/j.biopha.2016.11.098 215 MitchellM

While most peptide research programs begin with a specific therapeutic target and build a synthetic molecule to match, this compound emerged from a fundamentally different direction: isolation and characterization of a naturally occurring protective sequence, followed by decades of systematic investigation into its biological activity profile

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