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Here are some factors that can affect how quickly you notice results: Severity of Deficiency: Individuals with mild deficiencies may experience quick relief, but those with very low B12 levels might require several doses before a noticeable difference occurs

However, B12 shots can interact with some medications and are not recommended for people with certain conditions like kidney disorders

2008 Jan

A patient comes in for a flu shot and also needs a vitamin B12 injection

You may also find success with a GABA supplement, particularly if you struggle with anxiety

Vitamin B12 is water-soluble, and the kidneys pass the surplus into the urine rather than storing it