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Contact your GP or prescriber if you experience: Rectal bleeding , even if minorwhilst haemorrhoids are a common cause, bleeding always requires assessment to exclude more serious colorectal pathology Severe or persistent pain in the anal area that interferes with daily activities A lump or swelling near the anus that does not resolve within a few days Persistent constipation despite dietary modifications and over-the-counter laxatives Signs of anaemia (fatigue, pallor, breathlessness) if bleeding has been ongoing Severe, persistent abdominal pain , especially if radiating to the back (may indicate pancreatitis) Yellowing of the skin or eyes (jaundice), which could indicate gallbladder problems Seek urgent medical attention (contact 111 or attend A&E) if you develop: Severe rectal bleeding with large amounts of blood Excruciating anal pain suggesting thrombosed haemorrhoids or other acute anorectal conditions Signs of infection (fever, increasing pain, purulent discharge) Inability to pass stool (complete constipation) or severe abdominal pain Severe abdominal pain with vomiting that could indicate pancreatitis (a rare but serious side effect of Wegovy) Management approach : Your GP can diagnose haemorrhoids through history and examination

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Because B12 is a naturally occurring essential nutrient, your body recognizes and processes it efficiently

Semaglutide, a single-target, long-acting glucagon-like peptide-1 receptor agonist (GLP-1RA), has been shown to promote osteogenesis in vitro , but the underlying mechanism remains unclear

Monounsaturated and polyunsaturated fats may help support normal GLP-1 release while also contributing to heart health and overall metabolic wellness

Contact Newsweek editors on this story: Jason Lemon and Anthony Murray.