Advised dosage, in severe cases, is 600-1200 mg administered via intramuscular injection or intravenous drips
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Contraindications include pregnancy, active cancer, uncontrolled endocrine disorders, severe cardiovascular disease, and known peptide hypersensitivity
Fully reduced protein was incubated with indicated concentrations of APR-246 for one hour at 37 C and desalted with Amicon Ultra Centrifugal Spinners with 3000 cutoff for 30 min at 14000 g to remove excess compound
The most common injection areas are the stomach area near the belly button, front of thigh, and the side or back of upper arm
[PMID: 28345670] PubMed record related to this compound for laboratory literature review