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Learn more about Zepbound (tirzepatide) What is it: Zepbound (tirzepatide) is a weight-loss medication proven effective at managing blood sugars and promoting weight loss safely

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Your baseline metabolic ratethe calories your body burns at restdoesn't change significantly on semaglutide, but your total daily energy expenditure drops because you eat less and move less if appetite suppression is severe

Choe J, Archer JS, Shanks AL

As a result, it reduces any kind of oxidative damage to the cells