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16,51,52 Herniated discs trigger an innate and adaptive immune response with infiltration of macrophages, T and B cells, and the up-regulation of a myriad of pro-inflammatory cytokines, e.g., IL-1, IL-6, IL-8, IL-10, IL-17, IFN-, CCL2, TNF- and PGE2
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A novel nanoemulgel, formulated using microfibrillated cellulose derived from Argania spinosa shell and a rgan shell or a rgan press cake extracts, acts as a natural emulsifiers and increases melanin content successfully when compared to untreated B16F10 cells [21]
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