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Nat Commun (2012) 3:1271

10.1113/EP088434 Pubmed Abstract CrossRef Google Scholar View reference in article 4 BalintG

doi: 10.1016/j.redox.2022.102292 180 WuMYYiangGTLaiTTLiCJ

Metformin works primarily by reducing hepatic glucose production (the amount of glucose released by the liver), improving insulin sensitivity in peripheral tissues, and modestly enhancing glucose uptake in muscles