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In the absence of SIRT4, a failure to undergo cell cycle arrest induced by DNA damage causes a delay in DNA repair and increased chromosomal instability, suggesting a tumor suppressor effect of SIRT4 151

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People with active cancer should consult their oncologist before using any immunomodulatory peptide, including Ta1 (despite its use in cancer immunotherapy in some countries) and BPC-157 (due to angiogenesis promotion)

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