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[7] [8] GLP-1 receptor agonists (such as semaglutide, liraglutide, and dulaglutide) are now widely prescribed medications for type 2 diabetes and obesity management, approved by the MHRA and recommended in NICE guidelines (NG28 for type 2 diabetes

Insulin and leptin as adiposity signals

[14] successfully isolated exendin-4 from the venom of the Gila monster (Heloderma suspectum), a lizard known for its infrequent but large meals weighing up to as much as one third of its body masssuggesting the presence of adaptive metabolic mechanisms in the species [14,15]

Its not just about storage

In addition, despite great progress regarding the role of nonsense-mediated decay of SCN1A in disease modification [170, 171], there is still no approach to modify epilepsy in clinical practice

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