306 For example, the reduction in TNF-, IL-1, and IL-6 helps regulate local and systemic inflammatory responses
Orforglipron for the treatment of moderate-to-severe obstructive sleep apnea in adults with obesity or overweight: Study design and baseline characteristics of ATTAIN-OSA, a phase 3 trial, Contemporary Clinical Trials Communications, 52 , (101660), (2026)
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10.2337/diabetes.51.2.271
If shedding starts at months three to six, it is almost certainly telogen effluvium and it will resolve
Discuss with your clinician about temporarily slowing dose escalation if bloating is severe