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Defining this gutbrain lipid signaling pathway may reveal actionable therapeutic targets, including SCFA-dependent mTORC1 modulation and selective ISR/ATF4 pathway inhibition, for early prevention of BMP-associated neurodegenerative disorders

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Normal cells have low basal JNK activity to maintain optimal cellular growth conditions

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Acetaldehyde is classified as a possible human carcinogen and is estimated to be 10-30 times as toxic as alcohol