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GLP-1 therapies have revolutionised the management of type 2 diabetes and obesity

GLP-1Rs agonists exert neuro-humoral actions by stimulating insulin secretion and suppressing glucagon release in a glucose-dependent manner, delaying gastric emptying, and reducing appetite via central nervous system pathways

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Custer said overweight and obese patients with Type 2 diabetes are typically more resistant to weight loss than those without the condition

Prioritizing adequate protein intake and consistent hydration is essential to support healthy weight loss and protect lean muscle mass