It does this by inactivating it
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Side effects are uncommon and, when they occur, are typically mild, such as brief soreness at the injection site
After discovering DHODH, the same group identified another inner mitochondrial membrane-bound enzyme, glycerol-3-phosphate (G3P) dehydrogenase 2 (GPD2)
This mechanism does not broadly stimulate cell death but instead targets a survival dependency characteristic of senescent cells
Improvements were seen in patient ratings of tinnitus severity, annoyance, unpleasantness, and discomfort