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VTA, ventral tegmental area
The drug belongs to a class of drugs known as glucagon-like peptide 1 (GLP-1) agonists, which appear to mimic the feeling of being satiated, thereby seemingly suppressing appetite, too
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Loss of lean mass or functional decline suggests that nutritional support is inadequate relative to weight loss rate
When it is suppressed, muscle cells enter a catabolic state where protein breakdown exceeds protein creation
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