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The study suggests that the survival benefit of surgery is largely tied to how much weight patients shed, especially in the early years of diabetes when the body may still respond strongly to such changes

For patients with gastrointestinal intolerance, inadequate response to oral therapy, or ferritin 75-100 ng/mL with low transferrin saturation, intravenous iron (such as ferric carboxymaltose) may be considered

Changes in optic nerve head and retinal morphology during spaceflight and acute fluid shift reversal

However, they are usually temporary and often manageable

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especially when used in combination with healthier lifestyle choices