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They can cause oxidative stress, which triggers accelerated aging and increases your risk of cancer and diabetes ( However, spinach contains antioxidants, which fight oxidative stress and help reduce the damage it causes
Specifically, methylene tetrahydrofolate (THF) dehydrogenases catalyze the oxidation of 5,10-methylene-THF to form 10-formyl-THF, which is subsequently oxidized to CO 2 with concomitant NADPH production by 10-formyl-THF dehydrogenases (55)
The early hematopoietic gene HDD-2 localizes to 18Q12.1-12.2 and is not expressed in myeloid neoplasms
Huang, H
Nephron 1997
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