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it is not yet approved for use outside of research

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Reduced oral intake beyond just fluids may contribute to relative dehydration

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A complete understanding requires accounting for supplies, monitoring, consultations, and the less obvious expenses that accompany any serious medical intervention

54 Therefore, although we found that cinchonine lowered blood glucose and ameliorated NASH by activating GLP-1R, it cannot be excluded that it has other mechanisms to enhance or attenuate these effects