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NICE guidance and practical implications Based on this evidence, an SGLT2 inhibitor (dapagliflozin 10 mg once daily or empagliflozin 10 mg once daily) should be offered to all people with symptomatic HF (HFrEF or HFpEF), whether or not they have type 2 diabetes, unless contraindicated (Pop-Bussi et al, 2022)

Fortunately, these side effects typically fade within a few weeks as the body adjusts to the medication

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A deficiency in vitamin B12 results in an insufficiency of mature red blood cells containing haemoglobin, the oxygen carrying pigment that distributes oxygen to all the tissues around the body

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Expect surface adsorption losses at low concentration