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2 Mechanistic and biological pathways involving dietary supplements on oocytes The rising rates of infertility have stimulated interest in dietary supplements to improve oocyte quality through mitochondrial function, antioxidant activity, and epigenetically regulated metabolic pathways

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One exception is Lactobacillus plantarum and related lactobacilli, which use intracellular manganese to prevent damage from reactive O 2

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studies have shown that in a resting state, the GSH: GSSG ratio exceeds 100:1, while under oxidative stress, this ratio can decrease to 10:1 or lower