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Its particularly important for women of childbearing age, as it helps prevent neural tube defects in the developing fetus

The research brief recaps the discovery literature on selective androgen receptor modulation and emphasizes contexts where skeletal muscle and bone endpoints have been studied in preclinical systems, while also noting in vitro and neuronal model signals reported in the literature

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The body needs time to adjust, and making additional changes during this adjustment period complicates assessment

To conclude, the food intake reducing effects of exenatide may temporally evolve from strong anorectic to weak anhedonic modulations, where hedonic experience and anticipation during the early anorectic phase is conserved but uncoupled from food intake behaviour