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A multi-year open-label observational study in elderly patients reported improvements in self-reported sleep quality and physical performance scores, although study designs lacked blinding and modern placebo control

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Received: Accepted: Issue date: DOI:

Mobile phase A comprised water containing 0.1% formic acid and 5% acetonitrile and mobile phase B consisted of acetonitrile containing 0.1% formic acid and 5% water

Considering referral to NHS weight management services (tier 2 or 3) or dietetic support to help maintain weight loss